HIV/SIV infection primes monocytes and dendritic cells for apoptosis.
Subversion or exacerbation of antigen-presenting cells (APC) death modulates host/pathogen equilibrium.We demonstrated during in vitro differentiation of monocyte-derived macrophages Long Sleeve Polo and monocyte-derived dendritic cells (DCs) that HIV sensitizes the cells to undergo apoptosis in response to TRAIL and FasL, respectively.In addition,